NanoSpark™ GROW-NK
Soluble Activator – 2 mL

Description

The NanoSpark^TM GROW-NK Soluble Activator is a culture-ready, feeder-free reagent for in vitro activation and expansion of human NK cells. The nanoscale of the NanoSpark^TM GROW-NK protein complex allows for sterile filtration and removal of excess reagent via either media exchange or simple centrifugal cell washing.

First-in-Class GROW-NK Soluble Activator Removes Competing Feeder Cells and Bead-based Activators from NK Manufacturing

There is no other product like it. It’s simple, easy-to-use, and removes the need for costly, laborious, and risky feeder cells. Competing feeder cells introduce clinical risks to the process by contaminating cell therapies with cancer cells that could also harbor human pathogens.

The NanoSpark^TM product line is modular and plug-and-play by design, using a proprietary self-assembly protein nanoparticle complex that is inherently soluble and can be filter sterilized.

How Does the NanoSpark^TM GROW-NK Soluble Activator Work?

The NanoSpark^TM GROW-NK Soluble Activator contains self-assembling protein nanoparticles (complexes) with functional antibodies bound to the surface through high-affinity non-covalent interactions. These anti-NKp46 and anti-CD2 antibodies are arranged in a proprietary biophysical combination on the NanoSpark^TM platform that drives internal signal transduction or activation.

The NanoSpark^TM GROW-NK Soluble Activator activates resting donor human CD3-/CD56+ NK cells.

Inquire About Nanotein’s NK Activator

Need help getting started? Want to benefit most from your NK cell activation and expansion? Contact the Nanotein team today to learn more.

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  Convenient

  Soluble, feeder-free, protein-based, and ready-to-use.

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  High Performance

  Industry-leading feeder cell free NK expansion with high viability and cytotoxicity.

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  Reliable

  Employs anti-NKp46/CD2 antibodies displayed on our versatile NanoSpark^TM platform.